Paradoxical effects of KB-R7943 on arrhythmogenicity in a chronic myocardial infarction rabbit model
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چکیده
منابع مشابه
Effects of mesenchymal stem cells with injectable scaffold on cardiac function in myocardial infarction in Rabbit
BACKGROUND: Bone marrow-derived mesenchymal cellscan transdifferentiate into Cardiomyocyte cells and improveheart function after transplantation. Since biomaterials canimprove the cell retention in the site, cell survival and differentiation,heart tissue engineering is now being explored as anapplied solution to support cell-based therapies and increasetheir efficacy for myocardial diseases. Ch...
متن کاملEffects of caffeine, verapamil, lithium, and KB-R7943 on mechanics and energetics of rat myocardial bigeminies.
We examined the effects of pharmacological alteration of Ca2+ sources on mechanical and energetic properties of paired-pulse ("bigeminic") contractions. The fraction of heat release that is related to pressure development and pressure-independent heat release were measured during isovolumic contractions in arterially perfused rat ventricles. The heat released by regular and bigeminic contractio...
متن کاملTranslation of Methdology used in Human Myocardial Imaging to a Sheep Model of Acute Myocardial Infarction
Background: Pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. The aim of this study was to evaluate whether SPECT/CT myocardial perfusion imaging (MPI) could be used for assessing sheep myocardium following an acute myocardial infarction (MI) and response to int...
متن کاملeffects of mesenchymal stem cells with injectable scaffold on cardiac function in myocardial infarction in rabbit
background: bone marrow-derived mesenchymal cellscan transdifferentiate into cardiomyocyte cells and improveheart function after transplantation. since biomaterials canimprove the cell retention in the site, cell survival and differentiation,heart tissue engineering is now being explored as anapplied solution to support cell-based therapies and increasetheir efficacy for myocardial diseases. ch...
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Introduction: Today, improving patients’ quality of life (QOL) is the criterion for the treatment of coronary artery disease. The aim of this study was to evaluate the effect of spiritual care based on GHALBE SALIM model on QOL of acute myocardial infarction (AMI) patients. Materials and Methods: This single-blind clinical trial was conducted on 92 patients with AMI hospitalized in CCU of Chamr...
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ژورنال
عنوان ژورنال: Journal of Cardiology
سال: 2015
ISSN: 0914-5087
DOI: 10.1016/j.jjcc.2014.08.002